Blar i forfatter "Nedberg, Nora Hersoug"

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    • Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: A laboratory study using an in vitro model 

      Eksteen, Mariana; Heide, Gøril; Tiller, Heidi; Zhou, Yan; Nedberg, Nora Hersoug; Martinez-Zubiaurre, Inigo; Husebekk, Anne; Skogen, Bjørn Ragnar; Stuge, Tor Brynjar; Kjær, Mette (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-21)
      Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets. Antibodies against HPA-1a are accountable for the majority of FNAIT cases. We have previously shown that high levels of maternal anti-HPA-1a antibodies are associated with clinically significant reduced birth ...

    • Platelet alloimmunization is associated with low grade chronic histiocytic intervillositis - A new link to a rare placental lesion? 

      Nedberg, Nora Hersoug; Turowski, Gitta Erika; Guz, Katarzyna; Przytuła, Ewa; Uhrynowska, Małgorzata; Roald, Borghild; Husebekk, Anne; Sitras, Vasilis; Nystad, Mona; Dębska, Marzena; Brojer, Ewa; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
      <i>Introduction</i> - Maternal alloimmunization against human platelet antigen (HPA)-1a has been implied to mediate both reduced birth weight and chronic placental inflammation. Fetal growth restriction is associated with different types of chronic inflammation in the placenta, mainly chronic histiocytic intervillositis and chronic villitis. The aim of this prospective study was to do a systematic ...